Predicted to enable cell adhesion molecule binding activity. Predicted to be involved in cell adhesion and extracellular matrix organization. Predicted to be active in extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in congestive heart failure and corneal dystrophy (multiple). Orthologous to human POSTN (periostin) and TGFBI (transforming growth factor beta induced).
WB Description
The F26E4.7 gene encodes a homolog of human BIGH3, which when mutated leads to Groenouw granular dystrophy, type 1 (OMIM:122200).