Gene

F26E4.7

Species
Caenorhabditis elegans
Symbol
F26E4.7
Name
FAS1 domain-containing protein
Synonyms
  • CELE_F26E4.7
Biotype
protein coding gene
Automated Description
Predicted to enable cell adhesion molecule binding activity. Predicted to be involved in cell adhesion and extracellular matrix organization. Predicted to be active in extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in congestive heart failure and corneal dystrophy (multiple). Orthologous to human POSTN (periostin) and TGFBI (transforming growth factor beta induced).
WB Description
The F26E4.7 gene encodes a homolog of human BIGH3, which when mutated leads to Groenouw granular dystrophy, type 1 (OMIM:122200).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10900
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
9.7745M9.7750M9.7755M9.7760M9.7765M9.7770M9.7775M9.7780M9.7785M9.7790M9.7795M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions