Gene

phac-1

Species
Caenorhabditis elegans
Symbol
phac-1
Name
PHosphatase and ACtin regulator 1
Synonyms
  • CELE_F26H9.2
  • F26H9.2
Biotype
protein coding gene
Automated Description
Predicted to enable actin binding activity. Predicted to be involved in actin cytoskeleton organization. Is expressed in excretory cell; nervous system; and rectal epithelium. Human ortholog(s) of this gene implicated in Parkinson's disease; artery disease (multiple); brain disease (multiple); and multiple sclerosis. Orthologous to several human genes including PHACTR4 (phosphatase and actin regulator 4).
WB Description
Predicted to enable actin binding activity. Predicted to be involved in actin cytoskeleton organization. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); brain disease (multiple); and multiple sclerosis. Is an ortholog of human PHACTR4 (phosphatase and actin regulator 4).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12751
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
9.290M9.292M9.294M9.296M9.298M9.300M9.302M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions