Gene

gtf-2E2

Species
Caenorhabditis elegans
Symbol
gtf-2E2
Name
General Transcription Factor homolog 2E2
Synonyms
  • CELE_F54D5.11
  • F54D5.11
Biotype
protein coding gene
Automated Description
Enables RNA polymerase II complex binding activity. Involved in transcription initiation at RNA polymerase II promoter. Part of transcription factor TFIIE complex. Human ortholog(s) of this gene implicated in nonphotosensitive trichothiodystrophy 6. Orthologous to human GTF2E2 (general transcription factor IIE subunit 2).
WB Description
F54D5.11 encodes the C. elegans ortholog of the TFIIE beta subunit; when expressed in vitro with the TFIIE alpha subunit encoded by ZK550.4, the protein product of F54D5.11 supports transcription initiation; the protein products of F54D5.11 and ZK550.4 physically interact in vitro.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12716
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
11.5408M11.5410M11.5412M11.5414M11.5416M11.5418M11.5420M11.5422M11.5424M

Sequence Details

Transcript: Mode:

Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions