Gene

copz-1

Species
Caenorhabditis elegans
Symbol
copz-1
Name
COat Protein complex 1, Zeta subunit 1
Synonyms
  • CELE_F59E10.3
  • F59E10.3
Biotype
protein coding gene
Automated Description
Involved in embryo development; intracellular protein transport; and oocyte development. Predicted to be located in COPI-coated vesicle membrane and Golgi membrane. Predicted to be part of COPI vesicle coat. Orthologous to human COPZ1 (COPI coat complex subunit zeta 1) and COPZ2 (COPI coat complex subunit zeta 2).
WB Description
F59E10.3 encodes a zeta subunit of the coatomer (COPI) complex; in mass RNAi assays, F59E10.3 is required for embryonic, larval, and adult viability, for fertility, and for normal osmoregulation.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11043
No data available
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Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
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      Alleles and Variants

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        Transgenic Alleles

        Species
        (carrying the transgene)
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            WBcel235
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            10.8729M10.8730M10.8731M10.8732M10.8733M10.8734M10.8735M10.8736M10.8737M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            copz-1 molecule type
            Interactor gene
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              Genetic Interactions

              copz-1 role
              copz-1 genetic perturbation
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