Gene

zmp-5

Species
Caenorhabditis elegans
Symbol
zmp-5
Name
Zinc MetalloProtease 5
Synonyms
  • CELE_H36L18.1
  • H36L18.1
Biotype
protein coding gene
Automated Description
Predicted to enable metalloendopeptidase activity. Predicted to be involved in collagen catabolic process and extracellular matrix organization. Predicted to be located in extracellular matrix and membrane. Predicted to be active in extracellular space. Is expressed in dorsal uterine cell. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); arthritis (multiple); female reproductive organ cancer (multiple); obstructive lung disease (multiple); and scleroderma (multiple). Orthologous to several human genes including MMP16 (matrix metallopeptidase 16).
WB Description
Predicted to enable metalloendopeptidase activity. Predicted to be involved in collagen catabolic process and extracellular matrix organization. Predicted to be located in extracellular space. Expressed in dorsal uterine cell. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); and carcinoma (multiple). Is an ortholog of human MMP16 (matrix metallopeptidase 16).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10201
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
References
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    Transgenic Alleles

    Models

    Sequence Feature Viewer

    Genome location
    Assembly version
    WBcel235
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    12.6475M12.6480M12.6485M12.6490M12.6495M12.6500M12.6505M12.6510M

    Sequence Details

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    Expression

    Primary Sources
    Other Sources
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    Genetic Interactions