Predicted to enable metalloendopeptidase activity. Predicted to be involved in mitochondrial protein processing. Predicted to be located in mitochondrial inner membrane. Predicted to be part of m-AAA complex. Human ortholog(s) of this gene implicated in optic atrophy 11. Orthologous to human YME1L1 (YME1 like 1 ATPase).
WB Description
ymel-1 encodes an ortholog of human YME1L1 (OMIM:607472) and budding yeast Yme1p; YMEL-1 can suppress the formation of alpha-synuclein inclusions in older adults; on the basis of orthology, YMEL-1 is predicted to be an AAA protease of the mitochondrial inner membrane; however, YMEL-1 has no obvious function in mass RNAi assays.