Gene

agxt-1

Species
Caenorhabditis elegans
Symbol
agxt-1
Name
Alanine-GlyoXylate aminoTransferase 1
Synonyms
  • CELE_T14D7.1
  • T14D7.1
Biotype
protein coding gene
Automated Description
Enables alanine-glyoxylate transaminase activity. Involved in glycine biosynthetic process, by transamination of glyoxylate. Located in mitochondrion. Is expressed in body wall musculature and intestine. Human ortholog(s) of this gene implicated in primary hyperoxaluria type 1. Orthologous to human AGXT (alanine--glyoxylate aminotransferase).
WB Description
T14D7.1 is orthologous to the human gene ALANINE-GLYOXYLATE AMINOTRANSFERASE HOMOLOG (AGXT; OMIM:604285), which when mutated leads to disease.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR21152
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
8.8460M8.8465M8.8470M8.8475M8.8480M8.8485M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions