Gene

T23D8.3

Species
Caenorhabditis elegans
Symbol
T23D8.3
Name
Protein LTV1 homolog
Synonyms
  • CELE_T23D8.3
Biotype
protein coding gene
Automated Description
Predicted to be involved in ribosomal small subunit biogenesis and ribosomal small subunit export from nucleus. Predicted to be part of preribosome, small subunit precursor. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in inflammatory poikiloderma with hair abnormalities and acral keratoses. Orthologous to human LTV1 (LTV1 ribosome biogenesis factor).
WB Description
T23D8.3 encodes an ortholog of yeast and human LTV1 that inhibits DHC-1in vivo; in mass RNAi assays, T23D8.3 is required for embryonic andlarval development, normally large brood sizes, and normally fastgrowth.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR21531
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
9.9735M9.9740M9.9745M9.9750M9.9755M9.9760M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions