Predicted to be involved in ribosomal small subunit biogenesis and ribosomal small subunit export from nucleus. Predicted to be part of preribosome, small subunit precursor. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in inflammatory poikiloderma with hair abnormalities and acral keratoses. Orthologous to human LTV1 (LTV1 ribosome biogenesis factor).
WB Description
T23D8.3 encodes an ortholog of yeast and human LTV1 that inhibits DHC-1in vivo; in mass RNAi assays, T23D8.3 is required for embryonic andlarval development, normally large brood sizes, and normally fastgrowth.