Predicted to enable catalytic activity. Predicted to contribute to tRNA-specific adenosine-34 deaminase activity. Predicted to be active in cytoplasm and nucleus. Is expressed in pharyngeal gland cell and pm7. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with brain abnormalities, poor growth, and dysmorphic facies. Orthologous to human ADAT3 (adenosine deaminase tRNA specific 3).
WB Description
Y47D3A.14 encodes a cytosine deaminase orthologous to Saccharomyces cerevisiae Tad3p, a deaminase that lies, evolutionarily, between cytidine and adenosine deaminases and deaminates adenosine residues in the anticodon of specific yeast tRNAs.