Gene

eif-2Bbeta

Species
Caenorhabditis elegans
Symbol
eif-2Bbeta
Name
Eukaryotic Initiation Factor 2Bbeta
Synonyms
  • CELE_Y47H9C.7
  • Y47H9C.7
Biotype
protein coding gene
Automated Description
Predicted to enable translation initiation factor activity. Predicted to contribute to guanyl-nucleotide exchange factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytosol. Predicted to be part of eukaryotic translation initiation factor 2B complex. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter and leukoencephalopathy with vanishing white matter 2. Orthologous to human EIF2B2 (eukaryotic translation initiation factor 2B subunit beta).
WB Description
Y47H9C.7 is orthologous to the human gene EUKARYOTIC TRANSLATION INITIATION FACTOR 2B, SUBUNIT 2 (BETA, 39KD) (EIF2B2; OMIM:606454), which when mutated leads to disease.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45859
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
11.8916M11.8918M11.8920M11.8922M11.8924M11.8926M11.8928M11.8930M11.8932M11.8934M11.8936M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions