Predicted to enable translation initiation factor activity. Predicted to contribute to guanyl-nucleotide exchange factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytosol. Predicted to be part of eukaryotic translation initiation factor 2B complex. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter and leukoencephalopathy with vanishing white matter 2. Orthologous to human EIF2B2 (eukaryotic translation initiation factor 2B subunit beta).
WB Description
Y47H9C.7 is orthologous to the human gene EUKARYOTIC TRANSLATION INITIATION FACTOR 2B, SUBUNIT 2 (BETA, 39KD) (EIF2B2; OMIM:606454), which when mutated leads to disease.