Gene

Y57A10A.8

Species
Caenorhabditis elegans
Symbol
Y57A10A.8
Name
SPK domain-containing protein
Synonyms
  • CELE_Y57A10A.8
Biotype
protein coding gene
Automated Description
Not Available
WB Description
Enriched in PVR; germ line; germline precursor cell; rectal epithelial cell; and rectum based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including cyc-1; nuo-6; and atfs-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Peptidase C14A; SPK domain; and Domain of unknown function (DUF545).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23362
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
T28A8.6163349333 of 8  
T28A8.3262750333 of 8  
Y57A10A.5357753363 of 8  
T28A8.4450159393 of 8  
CD4.8557753323 of 8  
Y57A10A.4662246323 of 8  
B0212.3758648314 of 8  
M57.1856849324 of 8  
B0205.1951853354 of 8  
B0205.91058746284 of 8  
Y45F10C.11155144274 of 8  
Y57A10A.21250446333 of 8  
set-51360140253 of 8  
ZK402.51447348283 of 8  
set-241565936192 of 8  
R05D7.21650735233 of 8  
Y73B3B.11735948322 of 8  
T28A8.51837041263 of 8  
Y97E10AR.41945134192 of 8  
ZK402.12015147272 of 8  
ZK402.2218571512 of 8  
set-282218134192 of 8  
T28A8.8236068432 of 8  

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
No data available

Alleles and Variants

Genome location
Assembly version
WBcel235
Viewer Help
12.165M12.166M12.167M12.168M12.169M12.170M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_003280.10:g.12165936T>Gvariant
NC_003280.10:g.12168111A>Tvariant
NC_003280.10:g.12166172A>Tvariant
NC_003280.10:g.12168817A>Tvariant
NC_003280.10:g.12165082A>Tvariant
NC_003280.10:g.12168037T>Avariant
NC_003280.10:g.12166007C>Gvariant
NC_003280.10:g.12168106C>Avariant
NC_003280.10:g.12169185A>Tvariant
SNP
  • missense variant
NC_003280.10:g.12168152C>Tvariant
Showing 1 - 10 of 131 rows
per page

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
12.165M12.166M12.167M12.168M12.169M12.170MY57A10A.8.1 (Y57A10A.8)

Sequence Details

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Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

7 interactor genes based on 36 annotations
Y57A10A.8 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
magu-1Caenorhabditis elegans
protein
  • two hybrid
PMID:21110867
protein
mfsd-13.2Caenorhabditis elegans
protein
  • two hybrid
PMID:19123269
protein
set-18Caenorhabditis elegans
protein
  • two hybrid
PMID:14704431
protein
smo-1Caenorhabditis elegans
protein
  • two hybrid
PMID:19123269
protein
smo-1Caenorhabditis elegans
protein
  • affinity chromatography technology
PMID:19922876
protein
tdpt-1Caenorhabditis elegans
protein
  • two hybrid
PMID:14704431
protein
tdpt-1Caenorhabditis elegans
protein
  • two hybrid
PMID:14704431
protein
tdpt-1Caenorhabditis elegans
protein
  • two hybrid
PMID:14704431
protein
tdpt-1Caenorhabditis elegans
protein
  • two hybrid
PMID:14704431
protein
tdpt-1Caenorhabditis elegans
protein
  • two hybrid
PMID:14704431
Showing 1 - 10 of 36 rows
per page

Genetic Interactions

No data available