Gene

popl-7

Species
Caenorhabditis elegans
Symbol
popl-7
Name
POP ribonuclease P/MRP subunit Like 7
Synonyms
  • CELE_Y62E10A.2
  • Y62E10A.2
Biotype
protein coding gene
Automated Description
Predicted to be involved in intracellular transport and protein secretion. Predicted to be located in Golgi membrane. Orthologous to human TMEM167A (transmembrane protein 167A).
WB Description
Y62E10A.2 encodes an ortholog of Pop7 (Rpp20), a protein subunit sharedby the endoribonucleases RNase MRP and RNAse P; RNAse MRP cleavesmitochondrial RNA in mitochondrial DNA synthesis, nucleolar pre-rRNA inribosome synthesis, and at least one mRNA (CLB2) involved in cell-cycleregulation; RNAse P cleaves tRNA precursors to produce their mature 5'end; Y62E10A.2 may dissociate from the RNase MRP complex when it bindsto ribosomal precursors.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15314
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

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Other Sources
None
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
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      Alleles and Variants

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        Transgenic Alleles

        Species
        (carrying the transgene)
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            WBcel235
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            13.3707M13.3708M13.3709M13.3710M13.3711M13.3712M13.3713M13.3714M13.3715M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            popl-7 molecule type
            Interactor gene
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              Genetic Interactions

              popl-7 role
              popl-7 genetic perturbation
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