Gene

Y105E8B.7

Species
Caenorhabditis elegans
Symbol
Y105E8B.7
Name
Protein AF-9 homolog
Synonyms
  • CELE_Y105E8B.7
  • Y105E8B.f
Biotype
protein coding gene
Automated Description
Predicted to enable histone binding activity. Predicted to be involved in chromatin remodeling and regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be part of NuA4 histone acetyltransferase complex. Predicted to be active in nucleus. Orthologous to human MLLT1 (MLLT1 super elongation complex subunit) and MLLT3 (MLLT3 super elongation complex subunit).
WB Description
Predicted to enable histone binding activity. Predicted to be involved in chromatin remodeling and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of NuA4 histone acetyltransferase complex. Is an ortholog of human MLLT1 (MLLT1 super elongation complex subunit) and MLLT3 (MLLT3 super elongation complex subunit).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23195
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensMLLT12 of 9YesYes   
Homo sapiensMLLT32 of 9YesYes   
Mus musculusMllt12 of 9YesYes   
Mus musculusMllt32 of 9YesYes   
Rattus norvegicusMllt12 of 9YesYes   
Xenopus tropicalismllt32 of 9YesYes   
Danio reriomllt1b2 of 9YesYes   
Danio reriomllt1a2 of 9YesYes   
Saccharomyces cerevisiaeTAF142 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
gfl-1122552332 of 8  

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
all annotationsall disease by infectious agentbacterial infectious diseasefungal infectious diseaseparasitic infectious diseaseviral infectious diseaseall disease of anatomical entitycardiovascular system diseasecentral nervous system diseaseendocrine system diseasegastrointestinal system diseasehematopoietic system diseaseimmune system diseaseintegumentary system diseasemusculoskeletal system diseaseperipheral nervous system diseasereproductive system diseaserespiratory system diseasesensory system diseasethoracic diseaseurinary system diseaseall disease of cellular proliferationbenign neoplasmcancerpre-malignant neoplasmall genetic diseasechromosomal diseasemonogenic diseasepolygenic diseaseall other diseasedisease of mental healthdisease of metabolismphysical disordersyndrome
Y105E8B.7 (Cel)
Cell color indicative of annotation volume
No data available

Alleles and Variants

Genome location
Assembly version
WBcel235
Viewer Help
14.6430M14.6435M14.6440M14.6445M14.6450M14.6455M14.6460M14.6465M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_003279.8:g.14644283A>Gvariant
SNP
  • intron variant
NC_003279.8:g.14645358C>Tvariant
SNP
  • intron variant
NC_003279.8:g.14644812C>Tvariant
SNP
  • intron variant
NC_003279.8:g.14645103C>Tvariant
SNP
  • intron variant
NC_003279.8:g.14646383A>Tvariant
SNP
  • intron variant
NC_003279.8:g.14644968C>Tvariant
SNP
  • intron variant
NC_003279.8:g.14644164G>Avariant
SNP
  • missense variant
NC_003279.8:g.14646433T>Cvariant
SNP
  • synonymous variant
NC_003279.8:g.14645366C>Avariant
SNP
  • intron variant
NC_003279.8:g.14642857T>Avariant
SNP
  • intron variant
Showing 1 - 10 of 63 rows
per page

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
14.6430M14.6435M14.6440M14.6445M14.6450M14.6455M14.6460M14.6465MY105E8B.7.1 (Y105E8B.7)

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
all annotationsall anatomical structuresalimentary part of gastrointestinal systemchemosensory systemcirculatory systemendocrine systemexocrine systemhemolymphoid systemhepatobiliary systemintegumental systemmechanosensory systemmusculoskeletal systemnervous systemrenal systemreproductive systemrespiratory systemsensory systemvestibulo-auditory systemvisual systemendodermectodermmesodermmesenchymeadipose tissueappendageentire extraembryonic componentimaginal precursorpharyngeal archotherall stagesembryo stagepost embryonic, pre-adultpost-juvenile adult stageall cellular componentsextracellular regionplasma membranesynapsecell junctioncell projectioncytoplasmic vesicleendosomevacuolegolgi apparatusendoplasmic reticulumcytosolmitochondrionnucleuschromosomecytoskeletonprotein-containing complexother locations
Y105E8B.7 (Cel)
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

1 interactor gene based on 1 annotation
Y105E8B.7 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
affl-2Caenorhabditis elegans
protein
  • two hybrid
PMID:19123269
Showing 1 - 1 of 1 rows
per page

Genetic Interactions

No data available