Predicted to enable RNA binding activity and transcription termination site sequence-specific DNA binding activity. Predicted to be involved in termination of RNA polymerase II transcription. Predicted to be active in nuclear body. Is expressed in amphid neurons; gonad; and hypodermis. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 4; hypertension; and spinocerebellar ataxia with axonal neuropathy 2. Orthologous to human MOV10 (Mov10 RNA helicase) and SETX (senataxin).
WB Description
Predicted to enable RNA binding activity and transcription termination site sequence-specific DNA binding activity. Predicted to be involved in termination of RNA polymerase II transcription. Predicted to be located in nuclear body. Expressed in amphid neurons; gonad; and hypodermis. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 4; hypertension; and spinocerebellar ataxia with axonal neuropathy 2. Is an ortholog of human MOV10 (Mov10 RNA helicase) and SETX (senataxin).