Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in hematologic cancer (multiple); thrombocytopenia; and type 1 diabetes mellitus. Orthologous to several human genes including ETS1 (ETS proto-oncogene 1, transcription factor); ETS2 (ETS proto-oncogene 2, transcription factor); and ETV6 (ETS variant transcription factor 6).
WB Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in diabetes mellitus (multiple); hematologic cancer (multiple); and thrombocytopenia. Is an ortholog of several human genes including ETS1 (ETS proto-oncogene 1, transcription factor); ETS2 (ETS proto-oncogene 2, transcription factor); and ETV6 (ETS variant transcription factor 6).