Predicted to enable inorganic anion transmembrane transporter activity and organic anion transmembrane transporter activity. Predicted to be involved in chloride transmembrane transport and sulfate transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in pm3; pm4; pm5; pm6; and pm7. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 61 and spermatogenic failure 3. Orthologous to several human genes including SLC26A5 (solute carrier family 26 member 5); SLC26A6 (solute carrier family 26 member 6); and SLC26A7 (solute carrier family 26 member 7).
WB Description
sulp-3 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-3 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids; a sulp-3::GFP transcriptional fusion is expressed exclusively in the pharyngeal muscles.