Gene

dyla-1

Species
Caenorhabditis elegans
Symbol
dyla-1
Name
DYnein Light chain, Axonemal p28 type 1
Synonyms
  • CELE_F41G4.1
  • F41G4.1
Biotype
protein coding gene
Automated Description
Predicted to enable dynein heavy chain binding activity. Predicted to be located in cytoplasm. Predicted to be active in axoneme and ciliary base. Is expressed in head neurons. Human ortholog(s) of this gene implicated in spermatogenic failure 83. Orthologous to human DNALI1 (dynein axonemal light intermediate chain 1).
WB Description
Predicted to enable dynein heavy chain binding activity. Predicted to be located in axoneme and filopodium. Expressed in OLQDL; OLQDR; OLQVL; OLQVR; and head neurons. Human ortholog(s) of this gene implicated in spermatogenic failure. Is an ortholog of human DNALI1 (dynein axonemal light intermediate chain 1).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13183
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensDNALI17 of 9YesYes   
Mus musculusDnali17 of 9YesYes   
Rattus norvegicusDnali17 of 9YesYes   
Xenopus tropicalisdnali17 of 9YesYes   
Danio reriodnali18 of 9YesYes   
Drosophila melanogasterDnali17 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
WBcel235
Viewer Help
16.8412M16.8414M16.8416M16.8418M16.8420M16.8422M16.8424M16.8426M16.8428M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_003284.9:g.16841636G>Avariant
SNP
  • missense variant
NC_003284.9:g.16842572G>Avariant
SNP
  • splice region variant
NC_003284.9:g.16841412C>Tvariant
SNP
  • intron variant
NC_003284.9:g.16842775G>Avariant
SNP
  • missense variant
NC_003284.9:g.16841974A>Gvariant
SNP
  • intron variant
NC_003284.9:g.16842080G>Avariant
SNP
  • missense variant
NC_003284.9:g.16841077T>Cvariant
SNP
  • 5 prime UTR variant
NC_003284.9:g.16841133G>Avariant
SNP
  • missense variant
NC_003284.9:g.16841447T>Avariant
SNP
  • intron variant
NC_003284.9:g.16841754G>Avariant
SNP
  • intron variant
Showing 1 - 10 of 19 rows
per page

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
16.8412M16.8414M16.8416M16.8418M16.8420M16.8422M16.8424M16.8426M16.8428M

Sequence Details

Transcript: Mode:

Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

33 interactor genes based on 62 annotations
dyla-1 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
DNA
C46E10.8Caenorhabditis elegans
protein
  • one hybrid
PMID:24068555
DNA
C46E10.8Caenorhabditis elegans
protein
  • one hybrid
PMID:27777270
DNA
ceh-1Caenorhabditis elegans
protein
  • one hybrid
PMID:24068555
DNA
ceh-1Caenorhabditis elegans
protein
  • one hybrid
PMID:27777270
DNA
ceh-20Caenorhabditis elegans
protein
  • one hybrid
PMID:24068555
DNA
die-1Caenorhabditis elegans
protein
  • one hybrid
PMID:24068555
DNA
die-1Caenorhabditis elegans
protein
  • one hybrid
PMID:27777270
DNA
dmd-3Caenorhabditis elegans
protein
  • one hybrid
PMID:27777270
DNA
dmd-3Caenorhabditis elegans
protein
  • one hybrid
PMID:24068555
DNA
dmd-5Caenorhabditis elegans
protein
  • one hybrid
PMID:27777270
Showing 1 - 10 of 62 rows
per page

Genetic Interactions

No data available