Predicted to enable metalloendopeptidase activity. Predicted to be involved in peptide catabolic process and proteolysis involved in protein catabolic process. Predicted to be active in cytosol and mitochondrion. Is expressed in gonad. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Orthologous to human IDE (insulin degrading enzyme).
WB Description
Predicted to enable metalloendopeptidase activity. Predicted to be involved in peptide catabolic process and proteolysis involved in protein catabolic process. Predicted to be located in cytosol and mitochondrion. Expressed in gonad. Human ortholog(s) of this gene implicated in Alzheimer's disease; diabetic encephalopathy; and type 2 diabetes mellitus. Is an ortholog of human IDE (insulin degrading enzyme).