Kelch repeat and BTB domain-containing protein F47D12.7
Synonyms
CELE_F47D12.7
Biotype
protein coding gene
Automated Description
Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in spermatogenic failure 11. Orthologous to human KLHL10 (kelch like family member 10).
WB Description
Enriched in several structures, including VC neuron; anterior ganglion (post); germ line; hyp3; and interneuron based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including numr-2; numr-1; and mut-16 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-four chemicals including Heme; Ethanol; and nicotinic acid based on microarray and RNA-seq studies. Human ortholog(s) of this gene implicated in spermatogenic failure 11. Is predicted to encode a protein with the following domains: Kelch-type beta propeller; Kelch motif; Kelch repeat type 1; BTB/POZ domain; BTB-kelch protein; BTB/Kelch-associated; BTB And C-terminal Kelch; and SKP1/BTB/POZ domain superfamily. Is an ortholog of human KLHL10 (kelch like family member 10).