Gene

F47D12.7

Species
Caenorhabditis elegans
Symbol
F47D12.7
Name
Kelch repeat and BTB domain-containing protein F47D12.7
Synonyms
  • CELE_F47D12.7
Biotype
protein coding gene
Automated Description
Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in spermatogenic failure 11. Orthologous to human KLHL10 (kelch like family member 10).
WB Description
Enriched in several structures, including VC neuron; anterior ganglion (post); germ line; hyp3; and interneuron based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including numr-2; numr-1; and mut-16 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-four chemicals including Heme; Ethanol; and nicotinic acid based on microarray and RNA-seq studies. Human ortholog(s) of this gene implicated in spermatogenic failure 11. Is predicted to encode a protein with the following domains: Kelch-type beta propeller; Kelch motif; Kelch repeat type 1; BTB/POZ domain; BTB-kelch protein; BTB/Kelch-associated; BTB And C-terminal Kelch; and SKP1/BTB/POZ domain superfamily. Is an ortholog of human KLHL10 (kelch like family member 10).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24412
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
6.2935M6.2940M6.2945M6.2950M6.2955M6.2960M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions