Gene

snap-29

Species
Caenorhabditis elegans
Symbol
snap-29
Name
SNAP (Soluble NSF Attachment Protein) homolog 29
Synonyms
  • CELE_K02D10.5
  • K02D10.5
Biotype
protein coding gene
Automated Description
Predicted to enable SNAP receptor activity and syntaxin binding activity. Involved in intracellular protein transmembrane transport; ovulation; and secretion. Located in apical plasma membrane and recycling endosome. Is expressed in several structures, including coelomocyte; excretory canal; gland cell; hermaphrodite somatic gonadal cell; and vulva. Used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene implicated in CEDNIK syndrome. Orthologous to human SNAP29 (synaptosome associated protein 29).
WB Description
snap-29 encodes one of the SNAP25-family of double SNARE-domain target-SNAREs orthologous to human synaptosomal-Associated protein (OMIM:604202); snap-29 is an essential gene important for development and cellular functions throughout the life cycle; SNAP-29 is required for secretion of many transmembrane cargo proteins of oocyte cells; loss of SNAP-29 leads to defects in ovulation and RNAi leads to defects in maturation of distal oocytes; SNAP-29 is involved in membrane transport; SNAP-29 regulates LIN-3/EGF secretion in the oocyte which is essential for ovulation; SNAP-29 is expressed in excretory canal, gland cells, hypodermis, vulva, coelomocyte, intestine, gonad sheath cells and some neurons.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR19305
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
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8.7764M8.7766M8.7768M8.7770M8.7772M8.7774M8.7776M8.7778M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions