Gene

slmp-1

Species
Caenorhabditis elegans
Symbol
slmp-1
Name
SarcoLeMma associated Protein 1
Synonyms
  • CELE_M4.1
  • M4.1
Biotype
protein coding gene
Automated Description
Predicted to be involved in negative regulation of hippo signaling. Orthologous to several human genes including SLMAP (sarcolemma associated protein).
WB Description
Enriched in ABalappaap; ABprpapppa; AFD; germ line; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including atfs-1; hsf-1; and npr-1 based on microarray; RNA-seq; and proteomic studies. Is affected by nine chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: FHA domain; SMAD/FHA domain superfamily; Forkhead-associated (FHA) domain; and Centrosomal and Immune Signaling Modulators. Is an ortholog of human SLMAP (sarcolemma associated protein). Human SLMAP enables small GTPase binding activity.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15715
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
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      Variant
      Variant type
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
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          Models

          Model name
          Experimental condition
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            Sequence Feature Viewer

            Genome location
            Assembly version
            WBcel235
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            3.214M3.215M3.216M3.217M3.218M3.219M3.220M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            slmp-1 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
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              Genetic Interactions

              slmp-1 role
              slmp-1 genetic perturbation
              Interactor gene
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              Interactor role
              Interactor genetic perturbation
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              Phenotype or trait
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