Gene

gpx-6

Species
Caenorhabditis elegans
Symbol
gpx-6
Name
Glutathione PeroXidase 6
Synonyms
  • CELE_T09A12.2
  • T09A12.2
Biotype
protein coding gene
Automated Description
Predicted to enable peroxidase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. Predicted to be located in extracellular space. Is expressed in body wall musculature and nervous system. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma; colorectal cancer; and spondylometaphyseal dysplasia Sedaghatian type. Orthologous to human GPX4 (glutathione peroxidase 4).
WB Description
Predicted to enable peroxidase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); pre-eclampsia; and spondylometaphyseal dysplasia Sedaghatian type. Is an ortholog of human GPX4 (glutathione peroxidase 4).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11592
No data available
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Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
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    Transgenic Alleles

    Models

    Sequence Feature Viewer

    Genome location
    Assembly version
    WBcel235
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    8.2224M8.2226M8.2228M8.2230M8.2232M8.2234M

    Sequence Details

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    Expression

    Primary Sources
    Other Sources
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    Genetic Interactions