Gene

nmt-1

Species
Caenorhabditis elegans
Symbol
nmt-1
Name
N-Myristoyl Transferase homolog 1
Synonyms
  • CELE_T17E9.2
  • T17E9.2
Biotype
protein coding gene
Automated Description
Predicted to enable glycylpeptide N-tetradecanoyltransferase activity. Predicted to be involved in protein localization to membrane. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including anal depressor muscle; hypodermis; nervous system; pharynx; and reproductive system. Used to study muscular disease. Orthologous to human NMT1 (N-myristoyltransferase 1) and NMT2 (N-myristoyltransferase 2).
WB Description
nmt-1 encodes an N-myristoyl transferase; by homology, NMT-1 is predicted to catalyze the cotranslational attachment of myristate from CoA to the N-terminal glycine residue of proteins; in C. elegans, nmt-1 is widely expressed and required for a number of diverse processes, including development, locomotion, and apoptosis.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11377
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
6.1146M6.1148M6.1150M6.1152M6.1154M6.1156M6.1158M6.1160M6.1162M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions