Gene

ptpn-22

Species
Caenorhabditis elegans
Symbol
ptpn-22
Name
Protein Tyrosine Phosphatase Non-receptor type 22
Synonyms
  • CELE_Y41D4A.5
  • Y41D4A.5
Biotype
protein coding gene
Automated Description
Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in signal transduction. Human ortholog(s) of this gene implicated in several diseases, including Addison's disease; Meniere's disease; autoimmune disease (multiple); graft-versus-host disease; and pulmonary tuberculosis. Orthologous to several human genes including PTPN22 (protein tyrosine phosphatase non-receptor type 22).
WB Description
Predicted to enable protein tyrosine phosphatase activity. Human ortholog(s) of this gene implicated in several diseases, including Addison's disease; autoimmune disease (multiple); and graft-versus-host disease. Is an ortholog of human PTPN22 (protein tyrosine phosphatase non-receptor type 22).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR19134
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
1.728M1.730M1.732M1.734M1.736M1.738M1.740M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions