Gene

copa-1

Species
Caenorhabditis elegans
Symbol
copa-1
Name
COat Protein complex 1, Alpha subunit 1
Synonyms
  • CELE_Y71F9AL.17
  • Y71F9AL.17
Biotype
protein coding gene
Automated Description
Predicted to enable structural molecule activity. Predicted to be involved in Golgi vesicle transport and intracellular protein transport. Predicted to be located in COPI-coated vesicle membrane and Golgi membrane. Predicted to be part of COPI vesicle coat. Is expressed in several structures, including body wall musculature; intestine; pharynx; reproductive system; and seam cell. Human ortholog(s) of this gene implicated in autoimmune interstitial lung, joint, and kidney disease. Orthologous to human COPA (COPI coat complex subunit alpha).
WB Description
Y71F9AL.17 encodes an alpha subunit of the coatomer (COPI) complex; in mass RNAi assays, Y71F9AL.17 is required for embryonic viability, fertility, normal locomotion, and normally rapid growth.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR19876
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
2.8955M2.8960M2.8965M2.8970M2.8975M2.8980M2.8985M2.8990M2.8995M2.9000M2.9005M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions