Predicted to enable structural molecule activity. Predicted to be involved in Golgi vesicle transport and intracellular protein transport. Predicted to be located in COPI-coated vesicle membrane and Golgi membrane. Predicted to be part of COPI vesicle coat. Is expressed in several structures, including body wall musculature; intestine; pharynx; reproductive system; and seam cell. Human ortholog(s) of this gene implicated in autoimmune interstitial lung, joint, and kidney disease. Orthologous to human COPA (COPI coat complex subunit alpha).
WB Description
Y71F9AL.17 encodes an alpha subunit of the coatomer (COPI) complex; in mass RNAi assays, Y71F9AL.17 is required for embryonic viability, fertility, normal locomotion, and normally rapid growth.