Gene

chaf-2

Species
Caenorhabditis elegans
Symbol
chaf-2
Name
CHromatin Assembly Factor 2
Synonyms
  • CELE_Y71G12B.1
  • Y71G12B.1
Biotype
protein coding gene
Automated Description
Predicted to be involved in nucleosome assembly. Predicted to be part of CAF-1 complex. Predicted to be active in nucleus. Orthologous to human CHAF1B (chromatin assembly factor 1 subunit B).
WB Description
Predicted to be involved in nucleosome assembly. Predicted to be located in nucleus. Predicted to be part of CAF-1 complex. Human ortholog(s) of this gene implicated in several diseases, including glioblastoma; oral squamous cell carcinoma; and skin melanoma. Is an ortholog of human CHAF1B (chromatin assembly factor 1 subunit B).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15271
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
    Evidence
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    Based On
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
        Has Disease Annotations
        Has Phenotype Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
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            Sequence Feature Viewer

            Genome location
            Assembly version
            WBcel235
            Viewer Help
            1.8236M1.8238M1.8240M1.8242M1.8244M1.8246M1.8248M1.8250M1.8252M1.8254M1.8256M1.8258M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            chaf-2 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
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              Genetic Interactions

              chaf-2 role
              chaf-2 genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
              Source
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