Version: 8.1.0
Date: Fri Apr 18 2025
swsn-3
Caenorhabditis elegansWB:WBGene00022182
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

swsn-3

Species
Caenorhabditis elegans
Symbol
swsn-3
Name
SWI/SNF nucleosome remodeling complex component 3
Synonyms
  • CELE_Y71H2AM.17
  • Y71H2AM.17
Biotype
protein coding gene
Automated Description
Predicted to enable nuclear receptor binding activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of SWI/SNF complex. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 5; familial meningioma; and meningioma. Orthologous to human SMARCE1 (SWI/SNF related BAF chromatin remodeling complex subunit E1).
WB Description
Predicted to enable nuclear receptor binding activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of SWI/SNF complex. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 5 and familial meningioma. Is an ortholog of human SMARCE1 (SWI/SNF related BAF chromatin remodeling complex subunit E1).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46232
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          WBcel235
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          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          swsn-3 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection method
          Source
          Reference
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            Genetic Interactions

            swsn-3 role
            swsn-3 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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