Gene

gck-2

Species
Caenorhabditis elegans
Symbol
gck-2
Name
Germinal Center Kinase family 2
Synonyms
  • CELE_ZC404.9
  • ZC404.9
Biotype
protein coding gene
Automated Description
Predicted to enable MAP kinase kinase kinase kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm. Is expressed in several structures, including embryonic cell; excretory cell; intestine; reproductive system; and vulval precursor cell. Used to study ciliopathy. Orthologous to several human genes including MAP4K3 (mitogen-activated protein kinase kinase kinase kinase 3) and MAP4K5 (mitogen-activated protein kinase kinase kinase kinase 5).
WB Description
Predicted to enable MAP kinase kinase kinase kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in cytoplasm. Expressed in several structures, including embryonic cell and vulval precursor cell. Used to study ciliopathy. Is an ortholog of human MAP4K3 (mitogen-activated protein kinase kinase kinase kinase 3) and MAP4K5 (mitogen-activated protein kinase kinase kinase kinase 5).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR48012
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
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    Transgenic Alleles

    Models

    Sequence Feature Viewer

    Genome location
    Assembly version
    WBcel235
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    6.7885M6.7890M6.7895M6.7900M6.7905M6.7910M6.7915M6.7920M6.7925M

    Sequence Details

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    Expression

    Primary Sources
    Other Sources
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    Genetic Interactions