Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in neurons. Human ortholog(s) of this gene implicated in extrahepatic cholestasis; hepatocellular carcinoma; and progressive familial intrahepatic cholestasis 5. Orthologous to human NR1H4 (nuclear receptor subfamily 1 group H member 4) and NR1I3 (nuclear receptor subfamily 1 group I member 3).
WB Description
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in ASEL; ASER; and neurons. Human ortholog(s) of this gene implicated in cholestasis (multiple) and liver disease (multiple). Is an ortholog of human NR1H4 (nuclear receptor subfamily 1 group H member 4) and NR1I3 (nuclear receptor subfamily 1 group I member 3).