Predicted to enable [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity. Involved in heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi lumen. Is expressed in epithelial cell; hypodermis; neurons; and vulva. Human ortholog(s) of this gene implicated in colon cancer; hereditary angioedema; lung cancer; lung non-small cell carcinoma; and pancreatic cancer. Orthologous to several human genes including HS3ST2 (heparan sulfate-glucosamine 3-sulfotransferase 2).
WB Description
Predicted to enable [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity. Involved in heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi lumen. Expressed in epithelial cell; hypodermis; neurons; and vulva. Human ortholog(s) of this gene implicated in several diseases, including colon cancer; hereditary angioedema; and lung non-small cell carcinoma. Is an ortholog of human HS3ST2 (heparan sulfate-glucosamine 3-sulfotransferase 2).