Gene

hst-3.2

Species
Caenorhabditis elegans
Symbol
hst-3.2
Name
Heparan SulphoTransferase 3.2
Synonyms
  • CELE_F52B10.2
  • F52B10.2
Biotype
protein coding gene
Automated Description
Predicted to enable [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity. Involved in heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi lumen. Is expressed in epithelial cell; hypodermis; neurons; and vulva. Human ortholog(s) of this gene implicated in colon cancer; hereditary angioedema; lung cancer; lung non-small cell carcinoma; and pancreatic cancer. Orthologous to several human genes including HS3ST2 (heparan sulfate-glucosamine 3-sulfotransferase 2).
WB Description
Predicted to enable [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity. Involved in heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi lumen. Expressed in epithelial cell; hypodermis; neurons; and vulva. Human ortholog(s) of this gene implicated in several diseases, including colon cancer; hereditary angioedema; and lung non-small cell carcinoma. Is an ortholog of human HS3ST2 (heparan sulfate-glucosamine 3-sulfotransferase 2).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10605
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
2.9190M2.9195M2.9200M2.9205M2.9210M2.9215M2.9220M2.9225M2.9230M2.9235M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions