Predicted to enable G protein-coupled receptor activity and dopamine neurotransmitter receptor activity. Predicted to act upstream of or within adenylate cyclase-inhibiting dopamine receptor signaling pathway and regulation of secretion by cell. Predicted to be located in Golgi membrane and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; drug dependence (multiple); end stage renal disease; nicotine dependence; and type 2 diabetes mellitus. Orthologous to human DRD2 (dopamine receptor D2).