Gene

dct

Species
Xenopus tropicalis
Symbol
dct
Name
dopachrome tautomerase
Synonyms
  • dct
  • dopachrome tautomerase
Biotype
gene
Automated Description
Predicted to enable dopachrome isomerase activity. Predicted to be involved in several processes, including melanin biosynthetic process from tyrosine; positive regulation of neuroblast proliferation; and ventricular zone neuroblast division. Predicted to act upstream of or within melanin biosynthetic process. Predicted to be located in melanosome membrane. Predicted to be active in melanosome. Is expressed in dermal system; ectoderm; nervous system; and visual system. Human ortholog(s) of this gene implicated in oculocutaneous albinism. Orthologous to human DCT (dopachrome tautomerase).
XBXT Description
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensDCT5 of 9YesYes   
Mus musculusDct5 of 9YesYes   
Xenopus laevisdct.L1 of 1YesYes           
Danio reriodct5 of 9YesYes   
Caenorhabditis eleganstyr-43 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
tyrp1152664504 of 8  
tyr252160424 of 8  

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
XT9.1
Viewer Help
119.314M119.316M119.318M119.320M119.322M119.324MNM_001017161.2 (dct)XM_012957034.2 (dct)

Sequence Details

Transcript: Mode:

Expression

Primary Sources
Other Sources
None
all annotationsall anatomical structuresalimentary part of gastrointestinal systemchemosensory systemcirculatory systemendocrine systemexocrine systemhemolymphoid systemhepatobiliary systemintegumental systemmechanosensory systemmusculoskeletal systemnervous systemrenal systemreproductive systemrespiratory systemsensory systemvestibulo-auditory systemvisual systemendodermectodermmesodermmesenchymeadipose tissueappendageentire extraembryonic componentimaginal precursorpharyngeal archotherall stagesembryo stagepost embryonic, pre-adultpost-juvenile adult stageall cellular componentsextracellular regionplasma membranesynapsecell junctioncell projectioncytoplasmic vesicleendosomevacuolegolgi apparatusendoplasmic reticulumcytosolmitochondrionnucleuschromosomecytoskeletonprotein-containing complexother locations
dct (Xtr)
Dct (Mmu)
dct.L (Xla)
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions

No data available