Gene

nog

Species
Xenopus tropicalis
Symbol
nog
Name
noggin
Synonyms
  • nog
  • nog-A
Biotype
gene
Automated Description
Predicted to be involved in dorsal/ventral pattern formation; negative regulation of BMP signaling pathway; and osteoblast differentiation. Predicted to act upstream of or within cartilage development; cell differentiation; and negative regulation of cell differentiation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in musculoskeletal system; nervous system; pharyngeal arch; and primary germ layer. Human ortholog(s) of this gene implicated in Huntington's disease; bone disease (multiple); cleft lip; and hyperopia. Orthologous to human NOG (noggin).
XBXT Description
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensNOG9 of 9YesYes   
Mus musculusNog9 of 9YesYes   
Rattus norvegicusNog7 of 9YesYes   
Xenopus laevisnog.L1 of 1YesYes           
Xenopus laevisnog.S1 of 1YesYes           
Danio rerionog19 of 9YesYes   
Danio rerionog39 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
nog2121368522 of 8  
nog4218648312 of 8  

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
wholly ventralized embryo
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Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
XT9.1
Viewer Help
18.0488M18.0490M18.0492M18.0494M18.0496M18.0498M18.0500M18.0502MNM_001171898.1 (nog)XT-9_1-rna11157 (nog)

Sequence Details

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Expression

Primary Sources
Other Sources
None
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions

No data available