Predicted to be involved in establishment of mitotic spindle orientation and nuclear migration. Predicted to be located in cell cortex and microtubule. Predicted to be part of microtubule associated complex. Predicted to be active in axon; kinetochore; and spindle pole. Human ortholog(s) of this gene implicated in Perry syndrome; amyotrophic lateral sclerosis type 1; and autosomal dominant distal hereditary motor neuronopathy 14. Orthologous to human DCTN1 (dynactin subunit 1).
XBXT Description
cytoplasmic dynein-driven movement of organelles along microtubules [OMIM]