Version: 8.0.0
Date: Tue Jan 28 2025
cdk5.L
Xenopus laevisXenbase:XB-GENEPAGE-1010260
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

cdk5.L

Species
Xenopus laevis
Symbol
cdk5.L
Name
cyclin-dependent kinase 5
Synonyms
  • cdk5.L
  • cyclin-dependent kinase 5
Biotype
gene
Automated Description
Predicted to enable acetylcholine receptor activator activity; signaling receptor binding activity; and tau-protein kinase activity. Predicted to act upstream of or within neuron projection development; positive regulation of neuron apoptotic process; and regulation of dendritic spine morphogenesis. Predicted to be located in several cellular components, including growth cone; neuromuscular junction; and postsynaptic density. Human ortholog(s) of this gene implicated in Alzheimer's disease and lissencephaly 7 with cerebellar hypoplasia. Orthologous to human CDK5 (cyclin dependent kinase 5).
XBXL Description
early-expressed neuronal cyclin-dependent kinase
https://www.xenbase.org/gene/showgene.do?method=display&geneId=1010260
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
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      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
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          Sequence Feature Viewer

          Genome location
          Assembly version
          XL9.2
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          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          Other Sources
          None
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          cdk5.L molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            cdk5.L role
            cdk5.L genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
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