Gene

acta2.L

Species
Xenopus laevis
Symbol
acta2.L
Name
actin, alpha 2, smooth muscle, aorta
Synonyms
  • a-sma
  • aat6
Biotype
gene
Automated Description
Predicted to enable ATP binding activity and hydrolase activity. Predicted to act upstream of or within mesenchyme migration and positive regulation of gene expression. Predicted to be located in several cellular components, including cell body; filopodium; and lamellipodium. Is expressed in cardiovascular system; mesoderm; musculoskeletal system; and nervous system. Human ortholog(s) of this gene implicated in Moyamoya disease and thoracic aortic aneurysm. Orthologous to human ACTA2 (actin alpha 2, smooth muscle).
XBXL Description
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensACTA21 of 1YesYes           
Xenopus tropicalisacta21 of 1YesYes           
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
XL9.2
Viewer Help
6.935M6.936M6.937M6.938M6.939M6.940M6.941M6.942MNM_001091337.1 (acta2.L)XL-9_2-rna6148 (acta2.L)

Sequence Details

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Expression

Primary Sources
Other Sources
None
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions

No data available