Version: 8.0.0
Date: Tue Jan 28 2025
eftud2
Xenopus tropicalisXenbase:XB-GENE-972643
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

eftud2

Species
Xenopus tropicalis
Symbol
eftud2
Name
elongation factor Tu GTP binding domain containing 2
Synonyms
  • eftud2
  • elongation factor Tu GTP binding domain containing 2
Biotype
gene
Automated Description
Predicted to enable GTPase activity and U5 snRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of U2-type catalytic step 2 spliceosome and U4/U6 x U5 tri-snRNP complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in esophageal atresia; hepatitis B; hepatocellular carcinoma; mandibulofacial dysostosis, Guion-Almeida type; and microcephaly. Orthologous to human EFTUD2 (elongation factor Tu GTP binding domain containing 2).
XBXT Description
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
No data available

Alleles and Variants

Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
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    Transgenic Alleles

    No data available

    Models

    No data available

    Sequence Feature Viewer

    Genome location
    Assembly version
    XT9.1
    Viewer Help
    Data currently unavailable; sequence viewer under construction

    Sequence Details

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    Expression

    Primary Sources
    Other Sources
    None
    Must provide at least one subject
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    eftud2 molecule type
    Interactor gene
    Interactor species
    Interactor molecule type
    Detection methods
    Source
    Reference
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      Genetic Interactions

      No data available