Gene

sptb

Species
Danio rerio
Symbol
sptb
Name
spectrin, beta, erythrocytic
Synonyms
  • b-spectrin
  • fa09g12
Biotype
protein coding gene
Automated Description
Predicted to enable actin filament binding activity. Acts upstream of or within embryonic hemopoiesis and erythrocyte development. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be part of spectrin. Predicted to be active in several cellular components, including cell junction; cortical actin cytoskeleton; and plasma membrane. Is expressed in intermediate cell mass of mesoderm. Human ortholog(s) of this gene implicated in hereditary spherocytosis and hereditary spherocytosis type 2. Orthologous to human SPTB (spectrin beta, erythrocytic).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11915
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
38.570M38.575M38.580M38.585M38.590M38.595M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions