Gene

slc11a2

Species
Danio rerio
Symbol
slc11a2
Name
solute carrier family 11 member 2
Synonyms
  • cb426
  • cdy
Biotype
protein coding gene
Automated Description
Enables iron ion transmembrane transporter activity. Acts upstream of or within several processes, including embryonic hemopoiesis; hemoglobin biosynthetic process; and response to copper ion. Predicted to be located in late endosome membrane and lysosome. Predicted to be active in endosome membrane; lysosomal membrane; and plasma membrane. Is expressed in several structures, including alar plate midbrain region; digestive system; hematopoietic system; solid lens vesicle; and ventral mesoderm. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); autoimmune disease (multiple); inflammatory bowel disease (multiple); leishmaniasis (multiple); and tuberculosis (multiple). Orthologous to several human genes including SLC11A2 (solute carrier family 11 member 2).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
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Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions