Gene

pik3r1

Species
Danio rerio
Symbol
pik3r1
Name
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Synonyms
  • wu:fb65b05
Biotype
protein coding gene
Automated Description
Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity. Predicted to be involved in insulin receptor signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be part of phosphatidylinositol 3-kinase complex, class IA. Is expressed in eye and male organism. Human ortholog(s) of this gene implicated in several diseases, including SHORT syndrome; agammaglobulinemia 7; astroblastoma; endometrial cancer (multiple); and immunodeficiency 36. Orthologous to human PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10155
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
54.768M54.770M54.772M54.774M54.776M54.778M54.780M54.782M54.784M54.786M54.788M54.790M54.792M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions