Gene

hspb8

Species
Danio rerio
Symbol
hspb8
Name
heat shock protein b8
Synonyms
  • fc09c11
  • wu:fc04b04
Biotype
protein coding gene
Automated Description
Predicted to enable protein homodimerization activity. Predicted to be involved in cellular response to unfolded protein. Predicted to be part of protein folding chaperone complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including cephalic musculature; immature eye; midbrain hindbrain boundary neural rod; nervous system; and pericardial region. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2L and autosomal dominant distal hereditary motor neuronopathy 2. Orthologous to human HSPB8 (heat shock protein family B (small) member 8).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11527
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
15.820M15.822M15.824M15.826M15.828M15.830M15.832M15.834M15.836M15.838M15.840M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions