Version: 8.1.0
Date: Fri Apr 18 2025
rps14
Danio rerioZFIN:ZDB-GENE-030131-8631
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

rps14

Species
Danio rerio
Symbol
rps14
Name
ribosomal protein S14
Synonyms
  • fa92e08
  • wu:fa92e08
Biotype
protein coding gene
Automated Description
Predicted to be a structural constituent of ribosome. Acts upstream of or within chordate embryonic development and erythrocyte maturation. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Used to study chromosome 5q deletion syndrome. Human ortholog(s) of this gene implicated in chromosome 5q deletion syndrome. Orthologous to human RPS14 (ribosomal protein S14).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11759
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensRPS1410 of 10YesYes☑ ☑☑☑☑☑☑☑☑ ☑
Mus musculusRps1410 of 10YesYes☑ ☑☑☑☑☑☑☑☑ ☑
Rattus norvegicusRps149 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Rattus norvegicusLOC1201016504 of 9NoYes☐ ☐☐☐☑☐☑☑☑  
Xenopus tropicalisrps149 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Drosophila melanogasterRpS14a8 of 10YesYes☑ ☑☑☑☑☑☐☑☑ ☐
Drosophila melanogasterRpS14b8 of 10YesYes☑ ☑☑☑☑☑☐☑☑ ☐
Caenorhabditis elegansrps-149 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Saccharomyces cerevisiae S288CRPS14B9 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Saccharomyces cerevisiae S288CRPS14A9 of 9YesYes☑ ☑☑☑☑☑☑☑☑  

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
mrps11114946283 of 8☑ ☐☐☐☐☑☑☐ 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
anatomical structure central side lft1 expression mislocalised, abnormal
anatomical structure right side lft1 expression mislocalised, abnormal
apoptotic process increased occurrence, abnormal
blood hemoglobin decreased amount, abnormal
cranium edematous, abnormal
erythrocyte maturation decreased occurrence, abnormal
erythroid lineage cell hbae3 expression decreased amount, abnormal
erythroid lineage cell hbbe1.1 expression decreased amount, abnormal
erythroid lineage cell amount, normal
erythroid lineage cell decreased amount, abnormal
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Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
No data available

Alleles and Variants

Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
No records match query. Try removing filters.
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    Download all Alleles/Variants for all genes of the species

    Transgenic Alleles

    No data available

    Models

    Model name
    Experimental condition
    Associated Human Diseases
    Associated Phenotypes
    Modifier
    Source
    rps14zf624/zf624
    has condition:
    standard conditions
    • blood hemoglobin decreased amount, abnormal
    • whole organism mmp9 expression increased amount, abnormal
    		ZFIN
    AB + CRISPR1-rps14
    has condition:
    standard conditions
    • erythroid lineage cell decreased amount, abnormal
    		ZFIN
    AB + MO1-rps14
    has condition:
    chemical treatment L-leucine
    • whole organism cdkn1a expression increased amount, abnormal
    • whole organism tp53 expression increased amount, abnormal
    		ZFIN
    AB + MO1-rps14
    has condition:
    standard conditions
    • cranium edematous, abnormal
    • eye immature, abnormal
    		ZFIN
    rps14zf624/zf624
    has condition:
    chemical treatment by environment MMP9 inhibitor I
    • blood hemoglobin decreased amount, ameliorated
    		ZFIN
    rps14zf624/zf624
    has condition:
    chemical treatment by environment SB 431542
    • blood hemoglobin decreased amount, ameliorated
    		ZFIN
    rps14zf624/zf624
    has condition:
    chemical treatment by environment MMP-9-IN-1
    • blood hemoglobin decreased amount, ameliorated
    • brain necrotic, abnormal
    		ZFIN
    rps14zf624/zf624 (AB)
    has condition:
    standard conditions
    • erythroid lineage cell decreased amount, abnormal
    • head decreased size, abnormal
    		ZFIN
    rps14zf626/zf626 (AB)
    has condition:
    chemical treatment L-leucine
    • erythroid lineage cell amount, ameliorated
    		ZFIN
    rps14zf626/zf626 (AB)
    has condition:
    standard conditions
    • anatomical structure central side lft1 expression mislocalised, abnormal
    • anatomical structure right side lft1 expression mislocalised, abnormal
    		ZFIN
    Showing 1 - 10 of 14 rows
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    Sequence Feature Viewer

    No data available

    Sequence Details

    Transcript: Mode:

    Expression

    Primary Sources
    Other Sources
    Must provide at least one subject
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    No data available

    Genetic Interactions

    rps14 role
    rps14 genetic perturbation
    Interactor gene
    Interactor species
    Interactor role
    Interactor genetic perturbation
    Interaction type
    Phenotype or trait
    Source
    Reference
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