Enables peptidase activity. Involved in protein catabolic process. Predicted to be located in nucleolus. Predicted to be active in cytoplasm. Is expressed in brain; intestine; liver; and muscle. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy; autosomal recessive limb-girdle muscular dystrophy type 2A; and muscular dystrophy. Orthologous to human CAPN3 (calpain 3).