Gene

myoc

Species
Danio rerio
Symbol
myoc
Name
myocilin
Synonyms
  • zgc:136645
Biotype
protein coding gene
Automated Description
Predicted to enable metal ion binding activity. Acts upstream of or within female sex determination. Predicted to be located in several cellular components, including cilium; mitochondrial envelope; and rough endoplasmic reticulum. Predicted to be active in Golgi apparatus and extracellular space. Is expressed in caudal fin skeleton; eye; and postcranial axial skeleton. Human ortholog(s) of this gene implicated in juvenile glaucoma; low tension glaucoma; ocular hypertension; open-angle glaucoma; and primary open angle glaucoma. Orthologous to human MYOC (myocilin).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23192

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

No data available

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions