Gene

st8sia6

Species
Danio rerio
Symbol
st8sia6
Name
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
Synonyms
  • fa12f08
  • fb95c11
Biotype
protein coding gene
Automated Description
Predicted to enable alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity. Acts upstream of or within olfactory nerve formation and olfactory placode morphogenesis. Predicted to be located in Golgi membrane. Is expressed in several structures, including cardiovascular system; central nervous system; myotome; pleuroperitoneal region; and unfertilized egg. Orthologous to human ST8SIA6 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11987
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensST8SIA66 of 10YesYes  
Mus musculusSt8sia66 of 10YesYes  
Rattus norvegicusSt8sia68 of 9YesYes   
Xenopus tropicalisst8sia63 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
st8sia5132159375 of 8  
st8sia7.1231556375 of 8  
st8sia1335554383 of 8  
st8sia4437448284 of 8  
st8sia2533049324 of 8  
st8sia3629853344 of 8  

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
cranial nerve I axon mislocalised, abnormal
cranial nerve I morphology, abnormal
olfactory bulb glomerulus aplastic/hypoplastic, abnormal
olfactory nerve formation process quality, abnormal
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Disease Associations

Cases where the expected disease association was NOT found
all annotationsall disease by infectious agentbacterial infectious diseasefungal infectious diseaseparasitic infectious diseaseviral infectious diseaseall disease of anatomical entitycardiovascular system diseasecentral nervous system diseaseendocrine system diseasegastrointestinal system diseasehematopoietic system diseaseimmune system diseaseintegumentary system diseasemusculoskeletal system diseaseperipheral nervous system diseasereproductive system diseaserespiratory system diseasesensory system diseasethoracic diseaseurinary system diseaseall disease of cellular proliferationbenign neoplasmcancerpre-malignant neoplasmall genetic diseasechromosomal diseasemonogenic diseasepolygenic diseaseall other diseasedisease of mental healthdisease of metabolismphysical disordersyndrome
st8sia6 (Dre)
Cell color indicative of annotation volume
No data available

Alleles and Variants

Genome location
Assembly version
GRCz11
Viewer Help
16.266M16.268M16.270M16.272M16.274M16.276M16.278M16.280M16.282M16.284M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
sa33121allele with one associated variant
point mutation
  • splice donor variant
sa40026allele with one associated variant
point mutation
  • intron variant
sa18485allele with one associated variant
point mutation
  • intron variant
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Transgenic Alleles

No data available

Models

Model name
Experimental condition
Associated Human Diseases
Associated Phenotypes
Modifier
Source
rw034Tg; rw037Tg + MO1-st8sia6
has condition:
standard conditions
  • cranial nerve I axon mislocalised, abnormal
  • cranial nerve I morphology, abnormal
ZFIN
Showing 1 - 1 of 1 rows
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Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
16.266M16.268M16.270M16.272M16.274M16.276M16.278M16.280M16.282M16.284Mst8sia6-201 (st8sia6)bckdhbl-201 (bckdhbl)bckdhbl-202 (bckdhbl)bckdhbl-203 (bckdhbl)bckdhbl-204 (bckdhbl)

Sequence Details

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Expression

Primary Sources
Other Sources
all annotationsall anatomical structuresalimentary part of gastrointestinal systemchemosensory systemcirculatory systemendocrine systemexocrine systemhemolymphoid systemhepatobiliary systemintegumental systemmechanosensory systemmusculoskeletal systemnervous systemrenal systemreproductive systemrespiratory systemsensory systemvestibulo-auditory systemvisual systemendodermectodermmesodermmesenchymeadipose tissueappendageentire extraembryonic componentimaginal precursorpharyngeal archotherall stagesembryo stagepost embryonic, pre-adultpost-juvenile adult stageall cellular componentsextracellular regionplasma membranesynapsecell junctioncell projectioncytoplasmic vesicleendosomevacuolegolgi apparatusendoplasmic reticulumcytosolmitochondrionnucleuschromosomecytoskeletonprotein-containing complexother locations
st8sia6 (Dre)
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions

No data available