Version: 8.0.0Date: Tue Jan 28 2025
Gene
pja2
- Species
- Danio rerio
- Symbol
- pja2
- Name
- praja ring finger ubiquitin ligase 2
- Synonyms
- si:dkey-79c1.2
- Biotype
- protein coding gene
- Automated Description
- Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in membrane. Predicted to be active in cytoplasm. Is expressed in brain; head mesenchyme; post-vent vasculature; trunk vasculature; and yolk syncytial layer. Orthologous to several human genes including PJA2 (praja ring finger ubiquitin ligase 2).
- ZFIN Description
- Not Available
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR15710
Stringency:
Additional filters to further constrain the results:
| Species | Gene symbol | Count | Best | Best reverse | Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN |
|---|---|---|---|---|---|
| Homo sapiens | PJA2 | 9 of 10 | Yes | Yes | ☑ ☑☑☐☑☑☑☑☑ ☑ |
| Homo sapiens | PJA1 | 7 of 10 | No | Yes | ☐ ☑☑☐☑☑☑☑☑ ☐ |
| Mus musculus | Pja2 | 9 of 10 | Yes | Yes | ☑ ☑☑☐☑☑☑☑☑ ☑ |
| Mus musculus | Pja1 | 7 of 10 | No | Yes | ☐ ☑☑☐☑☑☑☑☑ ☐ |
| Rattus norvegicus | Pja2 | 7 of 9 | Yes | Yes | ☑ ☑☑☐☑☑☑☐☑ |
| Rattus norvegicus | Pja1 | 4 of 9 | No | Yes | ☐ ☑☐☐☑☑☑☐☐ |
| Xenopus tropicalis | pja2 | 8 of 9 | Yes | Yes | ☑ ☑☑☐☑☑☑☑☑ |
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Phenotypes
- Primary Sources
- Other Sources
- None
Phenotype Term | Annotation details | References |
|---|---|---|
| brain development disrupted, abnormal | ||
| embryo development disrupted, abnormal | ||
| head apoptotic, abnormal | ||
| head decreased size, abnormal | ||
| notochord morphology, abnormal | ||
| post-vent region decreased length, abnormal | ||
| post-vent region deformed, abnormal | ||
| post-vent region increased curvature, abnormal | ||
| somite shape, abnormal | ||
| whole organism increased curvature, abnormal |
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Disease Associations
Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species | Gene | Association | Disease Qualifier | Disease | Evidence | Source | Based On | References |
|---|---|---|---|---|---|---|---|---|
| No records match query. Try removing filters. | ||||||||
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Models
Model name | Experimental condition | Associated Human Diseases | Associated Phenotypes | Modifier | Source |
|---|---|---|---|---|---|
| WT + MO1-pja2 |
|
| ZFIN |
Showing 1 - 1 of 1 rows
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Sequence Feature Viewer
- Genome location
- Chr5:57210237...57234118 (23.88 kb)
- Assembly version
- GRCz11
- Viewer Help
Data currently unavailable; sequence viewer under construction