Gene

epas1b

Species
Danio rerio
Symbol
epas1b
Name
endothelial PAS domain protein 1b
Synonyms
  • epas1
  • hif-2a
Biotype
protein coding gene
Automated Description
Enables transcription cis-regulatory region binding activity. Acts upstream of or within several processes, including digestive system development; embryonic liver development; and hematopoietic stem cell differentiation. Predicted to be located in nucleus. Is expressed in several structures, including cardiovascular system; digestive system; musculature system; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in familial erythrocytosis 4; lung non-small cell carcinoma; polycythemia; and pulmonary hypertension. Orthologous to human EPAS1 (endothelial PAS domain protein 1).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23043
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
8.38M8.39M8.40M8.41M8.42M8.43M8.44M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions