Predicted to enable tRNA-intron endonuclease activity. Predicted to be involved in tRNA-type intron splice site recognition and cleavage. Predicted to act upstream of or within tRNA splicing, via endonucleolytic cleavage and ligation. Predicted to be located in nucleus. Predicted to be part of tRNA-intron endonuclease complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2B. Orthologous to human TSEN2 (tRNA splicing endonuclease subunit 2).