Gene

sgpl1

Species
Danio rerio
Symbol
sgpl1
Name
sphingosine-1-phosphate lyase 1
Synonyms
  • spl
  • zgc:162153
Biotype
protein coding gene
Automated Description
Predicted to enable sphinganine-1-phosphate aldolase activity. Predicted to be involved in sphingolipid catabolic process. Predicted to act upstream of or within carboxylic acid metabolic process. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including heart; intestine; kidney; liver; and yolk syncytial layer. Human ortholog(s) of this gene implicated in nephrotic syndrome type 14. Orthologous to human SGPL1 (sphingosine-1-phosphate lyase 1).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR42735
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
25.728M25.730M25.732M25.734M25.736M25.738M25.740M25.742M25.744M25.746M25.748M25.750M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions