Gene

glra1

Species
Danio rerio
Symbol
glra1
Name
glycine receptor, alpha 1
Synonyms
  • [a]Z1
  • GlyR [a]Z1
Biotype
protein coding gene
Automated Description
Enables extracellularly glycine-gated chloride channel activity and glycine binding activity. Acts upstream of or within several processes, including monoatomic ion transport; regulation of neuron differentiation; and response to amino acid. Located in membrane. Is expressed in brain; hindbrain; and spinal cord. Used to study hyperekplexia. Human ortholog(s) of this gene implicated in hyperekplexia 1. Orthologous to human GLRA1 (glycine receptor alpha 1).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR18945
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
25.82M25.83M25.84M25.85M25.86M25.87M25.88M25.89M25.90M25.91M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions